IKZF1 Alterations and Therapeutic Targeting in B-Cell Acute Lymphoblastic Leukemia
IKZF1 encodes the transcription factor IKAROS, a zinc finger DNA-binding protein with a key role in lymphoid lineage development. IKAROS plays a critical role in the development of lineage-restricted mature lymphocytes. Deletions within IKZF1 in B-cell acute lymphoblastic leukemia (B-ALL) lead to a...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Revisão |
| Langue: | anglais |
| Publié: |
2024
|
| Accès en ligne: | https://doi.org/10.3390/biomedicines12010089 https://www.mdpi.com/2227-9059/12/1/89/pdf?version=1704094659 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|