Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex

Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex

Abstract Abnormalities in neocortical and synaptic development are linked to neurodevelopmental disorders. However, the molecular and cellular mechanisms governing initial synapse formation in the prenatal neocortex remain poorly understood. Using polysome profiling coupled with snRNAseq on human co...

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Auteurs principaux: Iva Salamon, Yongkyu Park, Terezija Miškić, Janja Kopić, Paul G. Matteson, Nicholas F. Page, Alfonso Roque, Geoffrey McAuliffe, John Favate, Marta Garcia‐Forn, Premal Shah, Miloš Judáš, James H. Millonig, Ivica Kostović, Silvia De Rubeis, Ronald P. Hart, Željka Krsnik, Mladen‐Roko Rašin
Format: Artigo
Langue:anglais
Publié: 2023
Accès en ligne:https://doi.org/10.1038/s41467-023-41730-8
https://www.nature.com/articles/s41467-023-41730-8.pdf
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Internet

https://doi.org/10.1038/s41467-023-41730-8
https://www.nature.com/articles/s41467-023-41730-8.pdf

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