PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation

PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation

Abstract Multiple Sclerosis (MS) is a chronic autoimmune inflammatory disorder of the central nervous system (CNS). Current therapies mainly target inflammatory processes during acute stages, but effective treatments for progressive MS are limited. In this context, astrocytes have gained increasing...

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Hlavní autoři: Mathias Linnerbauer, Tobias A. Beyer, Lucy Nirschl, Daniel Farrenkopf, Lena Lößlein, Oliver Vandrey, Anne Peter, Thanos Tsaktanis, Hania Kébir, David Laplaud, Rupert Oellinger, Thomas Engleitner, Jorge I. Alvarez, Roland Rad, Thomas Korn, Bernhard Hemmer, Francisco J. Quintana, Veit Rothhammer
Médium: Artigo
Jazyk:angličtina
Vydáno: 2023
On-line přístup:https://doi.org/10.1038/s41467-023-40982-8
https://www.nature.com/articles/s41467-023-40982-8.pdf
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https://doi.org/10.1038/s41467-023-40982-8
https://www.nature.com/articles/s41467-023-40982-8.pdf

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