Combining protein sequences and structures with transformers and equivariant graph neural networks to predict protein function

Abstract Motivation Millions of protein sequences have been generated by numerous genome and transcriptome sequencing projects. However, experimentally determining the function of the proteins is still a time consuming, low-throughput, and expensive process, leading to a large protein sequence-funct...

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Hlavní autoři: Frimpong Boadu, Hongyuan Cao, Jianlin Cheng
Médium: Artigo
Jazyk:angličtina
Vydáno: 2023
On-line přístup:https://doi.org/10.1093/bioinformatics/btad208
https://academic.oup.com/bioinformatics/article-pdf/39/Supplement_1/i318/50741489/btad208.pdf
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