Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes

Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes

Abstract Major depressive disorder (MDD) is a common, heterogenous, and potentially serious psychiatric illness. Diverse brain cell types have been implicated in MDD etiology. Significant sexual differences exist in MDD clinical presentation and outcome, and recent evidence suggests different molecu...

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Main Authors: Malosree Maitra, Haruka Mitsuhashi, Reza Rahimian, Anjali Chawla, Jennie Yang, Laura M. Fiori, Maria Antonietta Davoli, Kelly Perlman, Zahia Aouabed, Deborah C. Mash, Matthew Suderman, Naguib Mechawar, Gustavo Turecki, Corina Nagy
Format: Revisão
Language:English
Published: 2023
Online Access:https://doi.org/10.1038/s41467-023-38530-5
https://www.nature.com/articles/s41467-023-38530-5.pdf
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https://doi.org/10.1038/s41467-023-38530-5
https://www.nature.com/articles/s41467-023-38530-5.pdf

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