A dual-action niclosamide-based prodrug that targets cancer stem cells and inhibits TNBC metastasis

Chemotherapy typically destroys the tumor mass but rarely eradicates the cancer stem cells (CSCs) that can drive metastatic recurrence. A key current challenge is finding ways to eradicate CSCs and suppress their characteristics. Here, we report a prodrug, Nic-A, created by combining a carbonic anhy...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Ji Hyeon Kim, Soeun Park, Eunsun Jung, Jin Woo Shin, Yoon-Jae Kim, Ji Young Kim, Jonathan L. Sessler, Jae Hong Seo, Jong Seung Kim
Формат: Artigo
Хэл сонгох:англи
Хэвлэсэн: 2023
Онлайн хандалт:https://doi.org/10.1073/pnas.2304081120
Шошгууд: Шошго нэмэх
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!