A dual-action niclosamide-based prodrug that targets cancer stem cells and inhibits TNBC metastasis
Chemotherapy typically destroys the tumor mass but rarely eradicates the cancer stem cells (CSCs) that can drive metastatic recurrence. A key current challenge is finding ways to eradicate CSCs and suppress their characteristics. Here, we report a prodrug, Nic-A, created by combining a carbonic anhy...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | inglese |
| Pubblicazione: |
2023
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| Accesso online: | https://doi.org/10.1073/pnas.2304081120 |
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