A dual-action niclosamide-based prodrug that targets cancer stem cells and inhibits TNBC metastasis

Chemotherapy typically destroys the tumor mass but rarely eradicates the cancer stem cells (CSCs) that can drive metastatic recurrence. A key current challenge is finding ways to eradicate CSCs and suppress their characteristics. Here, we report a prodrug, Nic-A, created by combining a carbonic anhy...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ji Hyeon Kim, Soeun Park, Eunsun Jung, Jin Woo Shin, Yoon-Jae Kim, Ji Young Kim, Jonathan L. Sessler, Jae Hong Seo, Jong Seung Kim
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2023
Mynediad Ar-lein:https://doi.org/10.1073/pnas.2304081120
Tagiau: Ychwanegu Tag
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