A dual-action niclosamide-based prodrug that targets cancer stem cells and inhibits TNBC metastasis

A dual-action niclosamide-based prodrug that targets cancer stem cells and inhibits TNBC metastasis

Chemotherapy typically destroys the tumor mass but rarely eradicates the cancer stem cells (CSCs) that can drive metastatic recurrence. A key current challenge is finding ways to eradicate CSCs and suppress their characteristics. Here, we report a prodrug, Nic-A, created by combining a carbonic anhy...

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Main Authors:	Ji Hyeon Kim, Soeun Park, Eunsun Jung, Jin Woo Shin, Yoon-Jae Kim, Ji Young Kim, Jonathan L. Sessler, Jae Hong Seo, Jong Seung Kim
格式:	Artigo
语言:	英语
出版:	2023
在线阅读:	https://doi.org/10.1073/pnas.2304081120
标签:	添加标签没有标签, 成为第一个标记此记录!

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