A dual-action niclosamide-based prodrug that targets cancer stem cells and inhibits TNBC metastasis
Chemotherapy typically destroys the tumor mass but rarely eradicates the cancer stem cells (CSCs) that can drive metastatic recurrence. A key current challenge is finding ways to eradicate CSCs and suppress their characteristics. Here, we report a prodrug, Nic-A, created by combining a carbonic anhy...
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Hlavní autoři: | Ji Hyeon Kim, Soeun Park, Eunsun Jung, Jin Woo Shin, Yoon-Jae Kim, Ji Young Kim, Jonathan L. Sessler, Jae Hong Seo, Jong Seung Kim |
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Médium: | Artigo |
Jazyk: | angličtina |
Vydáno: |
2023
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On-line přístup: | https://doi.org/10.1073/pnas.2304081120 |
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