Role of condensates in modulating DNA repair pathways and its implication for chemoresistance

For cells, it is important to repair DNA damage, such as double-strand and single-strand DNA breaks, because unrepaired DNA can compromise genetic integrity, potentially leading to cell death or cancer. Cells have multiple DNA damage repair pathways that have been the subject of detailed genetic, bi...

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Main Authors: Giuseppe Dall’Agnese, Alessandra Dall’Agnese, Salman F. Banani, Marta Codrich, Matilde Clarissa Malfatti, Giulia Antoniali, Gianluca Tell
格式: Revisão
语言:英语
出版: 2023
在线阅读:https://doi.org/10.1016/j.jbc.2023.104800
http://www.jbc.org/article/S0021925823018288/pdf
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