Role of condensates in modulating DNA repair pathways and its implication for chemoresistance
For cells, it is important to repair DNA damage, such as double-strand and single-strand DNA breaks, because unrepaired DNA can compromise genetic integrity, potentially leading to cell death or cancer. Cells have multiple DNA damage repair pathways that have been the subject of detailed genetic, bi...
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Main Authors: | , , , , , , |
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格式: | Revisão |
语言: | 英语 |
出版: |
2023
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在线阅读: | https://doi.org/10.1016/j.jbc.2023.104800 http://www.jbc.org/article/S0021925823018288/pdf |
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