Role of condensates in modulating DNA repair pathways and its implication for chemoresistance

For cells, it is important to repair DNA damage, such as double-strand and single-strand DNA breaks, because unrepaired DNA can compromise genetic integrity, potentially leading to cell death or cancer. Cells have multiple DNA damage repair pathways that have been the subject of detailed genetic, bi...

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Hlavní autoři: Giuseppe Dall’Agnese, Alessandra Dall’Agnese, Salman F. Banani, Marta Codrich, Matilde Clarissa Malfatti, Giulia Antoniali, Gianluca Tell
Médium: Revisão
Jazyk:angličtina
Vydáno: 2023
On-line přístup:https://doi.org/10.1016/j.jbc.2023.104800
http://www.jbc.org/article/S0021925823018288/pdf
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