<i>TP53</i> Gain-of-Function and Non–Gain-of-Function Mutations Are Associated With Differential Prognosis in Advanced Pancreatic Ductal Adenocarcinoma
PURPOSE To examine the impact of TP53 gain-of-function (GOF) and non-GOF mutations on prognosis of advanced pancreatic ductal adenocarcinoma (PDAC) among patients with KRAS, CDKN2A, and SMAD4 comutations. METHODS This cohort included patients with locally advanced, recurrent, and de novo metastatic...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | inglese |
| Pubblicazione: |
2023
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| Accesso online: | https://doi.org/10.1200/po.22.00570 |
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