<i>TP53</i> Gain-of-Function and Non–Gain-of-Function Mutations Are Associated With Differential Prognosis in Advanced Pancreatic Ductal Adenocarcinoma

<i>TP53</i> Gain-of-Function and Non–Gain-of-Function Mutations Are Associated With Differential Prognosis in Advanced Pancreatic Ductal Adenocarcinoma

PURPOSE To examine the impact of TP53 gain-of-function (GOF) and non-GOF mutations on prognosis of advanced pancreatic ductal adenocarcinoma (PDAC) among patients with KRAS, CDKN2A, and SMAD4 comutations. METHODS This cohort included patients with locally advanced, recurrent, and de novo metastatic...

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Päätekijät: Minggui Pan, Chen Jiang, Zheyang Zhang, Ninah Achacoso, Stacey E. Alexeeff, Aleyda V. Solorzano, Pam Tse, Elaine Chung, Tilak Sundaresan, Jennifer M. Suga, Sachdev Thomas, Laurel A. Habel
Aineistotyyppi: Artigo
Kieli:englanti
Julkaistu: 2023
Linkit:https://doi.org/10.1200/po.22.00570
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Internet

https://doi.org/10.1200/po.22.00570

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