Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities

Closely associated with aging and age-related disorders, cellular senescence (CS) is the inability of cells to proliferate due to accumulated unrepaired cellular damage and irreversible cell cycle arrest. Senescent cells are characterized by their senescence-associated secretory phenotype that overp...

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Main Authors: Prashanta Silwal, Allison M. Nguyen-Thai, Haneef Ahamed Mohammad, Yanshan Wang, Paul D. Robbins, Joon Y. Lee, Nam V. Vo
格式: Revisão
語言:英语
出版: 2023
在線閱讀:https://doi.org/10.3390/biom13040686
https://www.mdpi.com/2218-273X/13/4/686/pdf?version=1681804094
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