Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities
Closely associated with aging and age-related disorders, cellular senescence (CS) is the inability of cells to proliferate due to accumulated unrepaired cellular damage and irreversible cell cycle arrest. Senescent cells are characterized by their senescence-associated secretory phenotype that overp...
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Main Authors: | , , , , , , |
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Format: | Revisão |
Language: | English |
Published: |
2023
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Online Access: | https://doi.org/10.3390/biom13040686 https://www.mdpi.com/2218-273X/13/4/686/pdf?version=1681804094 |
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