Hydrogel armed with Bmp2 mRNA-enriched exosomes enhances bone regeneration
Sustained release of bioactive BMP2 (bone morphogenetic protein-2) is important for bone regeneration, while the intrinsic short half-life of BMP2 at protein level cannot meet the clinical need. In this study, we aimed to design Bmp2 mRNA-enriched engineered exosomes, which were then loaded into spe...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | anglès |
| Publicat: |
2023
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| Accés en línia: | https://doi.org/10.1186/s12951-023-01871-w https://jnanobiotechnology.biomedcentral.com/counter/pdf/10.1186/s12951-023-01871-w |
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