Hydrogel armed with Bmp2 mRNA-enriched exosomes enhances bone regeneration
Sustained release of bioactive BMP2 (bone morphogenetic protein-2) is important for bone regeneration, while the intrinsic short half-life of BMP2 at protein level cannot meet the clinical need. In this study, we aimed to design Bmp2 mRNA-enriched engineered exosomes, which were then loaded into spe...
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| Main Authors: | , , , , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2023
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| 在線閱讀: | https://doi.org/10.1186/s12951-023-01871-w https://jnanobiotechnology.biomedcentral.com/counter/pdf/10.1186/s12951-023-01871-w |
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