The CLDN5 gene at the blood-brain barrier in health and disease

Abstract The CLDN5 gene encodes claudin-5 (CLDN-5) that is expressed in endothelial cells and forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain barrier (BBB), composed of brain microvascular endothelial cells and associated pericytes and end-feet of astroc...

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Main Authors: Yosuke Hashimoto, Chris Greene, Arnold Münnich, Matthew Campbell
格式: Revisão
语言:英语
出版: 2023
在线阅读:https://doi.org/10.1186/s12987-023-00424-5
https://fluidsbarrierscns.biomedcentral.com/counter/pdf/10.1186/s12987-023-00424-5
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