The CLDN5 gene at the blood-brain barrier in health and disease

Abstract The CLDN5 gene encodes claudin-5 (CLDN-5) that is expressed in endothelial cells and forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain barrier (BBB), composed of brain microvascular endothelial cells and associated pericytes and end-feet of astroc...

Full description

Saved in:
Bibliographic Details
Main Authors: Yosuke Hashimoto, Chris Greene, Arnold Münnich, Matthew Campbell
Format: Revisão
Language:English
Published: 2023
Online Access:https://doi.org/10.1186/s12987-023-00424-5
https://fluidsbarrierscns.biomedcentral.com/counter/pdf/10.1186/s12987-023-00424-5
Tags: Add Tag
No Tags, Be the first to tag this record!