Loco-regional treatment with temozolomide-loaded thermogels prevents glioblastoma recurrences in orthotopic human xenograft models

Glioblastoma multiforme (GBM) is the most aggressive primary tumor of the central nervous system and the diagnosis is often dismal. GBM pharmacological treatment is strongly limited by its intracranial location beyond the blood-brain barrier (BBB). While Temozolomide (TMZ) exhibits the best clinical...

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Bibliografiset tiedot
Päätekijät: Lisa Gherardini, Veronica Vetri Buratti, Mirko Maturi, Giovanni Inzalaco, Erica Locatelli, Letizia Sambri, Sara Gargiulo, Virginia Barone, Denise Bonente, Eugenio Bertelli, Silvia Tortorella, Lorenzo Franci, A. Fioravanti, Mauro Comes Franchini, M Chiariello
Aineistotyyppi: Artigo
Kieli:englanti
Julkaistu: 2023
Linkit:https://doi.org/10.1038/s41598-023-31811-5
https://www.nature.com/articles/s41598-023-31811-5.pdf
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