Functional SARS-CoV-2 cross-reactive CD4 <sup>+</sup> T cells established in early childhood decline with age

Pre-existing SARS-CoV-2-reactive T cells have been identified in SARS-CoV-2-unexposed individuals, potentially modulating COVID-19 and vaccination outcomes. Here, we provide evidence that functional cross-reactive memory CD4 + T cell immunity against severe acute respiratory syndrome coronavirus 2 (...

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Main Authors: Marion Humbert, Anna Olofsson, David Wullimann, Julia Niessl, Emma B. Hodcroft, Curtis Cai, Yu Gao, Ebba Sohlberg, Robert Dyrdak, Flora Mikaeloff, Ujjwal Neogi, Jan Albert, Karl‐Johan Malmberg, Fridtjof Lund‐Johansen, Soo Aleman, Linda Björkhem‐Bergman, Maria C. Jenmalm, Hans‐Gustaf Ljunggren, Marcus Buggert, Annika C. Karlsson
格式: Artigo
语言:英语
出版: 2023
在线阅读:https://doi.org/10.1073/pnas.2220320120
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