Functional SARS-CoV-2 cross-reactive CD4 <sup>+</sup> T cells established in early childhood decline with age

Functional SARS-CoV-2 cross-reactive CD4 <sup>+</sup> T cells established in early childhood decline with age

Pre-existing SARS-CoV-2-reactive T cells have been identified in SARS-CoV-2-unexposed individuals, potentially modulating COVID-19 and vaccination outcomes. Here, we provide evidence that functional cross-reactive memory CD4 + T cell immunity against severe acute respiratory syndrome coronavirus 2 (...

Full description

Saved in:
Bibliographic Details
Main Authors: Marion Humbert, Anna Olofsson, David Wullimann, Julia Niessl, Emma B. Hodcroft, Curtis Cai, Yu Gao, Ebba Sohlberg, Robert Dyrdak, Flora Mikaeloff, Ujjwal Neogi, Jan Albert, Karl‐Johan Malmberg, Fridtjof Lund‐Johansen, Soo Aleman, Linda Björkhem‐Bergman, Maria C. Jenmalm, Hans‐Gustaf Ljunggren, Marcus Buggert, Annika C. Karlsson
Format: Artigo
Language:English
Published: 2023
Online Access:https://doi.org/10.1073/pnas.2220320120
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1073/pnas.2220320120

Similar Items