Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer

Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer

Abstract Programmed death-1 (PD-1) and its ligand programmed death-ligand 1 (PD-L1) help tumor cells evade immune surveillance, and are regarded as important targets of anti-tumor immunotherapy. Post-translational modification of PD-L1 has potential value in immunosuppression. Here, we identified th...

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Bibliografiske detaljer
Main Authors: Hanshen Yang, Xiaozhen Zhang, Mengyi Lao, Kang Sun, Lihong He, Jian Xu, Yi Duan, Yan Chen, Honggang Ying, Muchun Li, Chengxiang Guo, Qingsong Lu, Sicheng Wang, Wei Su, Tingbo Liang, Xueli Bai
Format: Artigo
Sprog:engelsk
Udgivet: 2022
Online adgang:https://doi.org/10.1038/s41418-022-01102-z
https://www.nature.com/articles/s41418-022-01102-z.pdf
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https://doi.org/10.1038/s41418-022-01102-z
https://www.nature.com/articles/s41418-022-01102-z.pdf

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