The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

Abstract Histone 3 lysine27-to-methionine (H3-K27M) mutations most frequently occur in diffuse midline gliomas (DMGs) of the childhood pons but are also increasingly recognized in adults. Their potential heterogeneity at different ages and midline locations is vastly understudied. Here, through diss...

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Hlavní autoři: Ilon Liu, Li Jiang, Erik Samuelsson, Sergio Marco Salas, Alexander Beck, Olivia A. Hack, Da-Eun Jeong, McKenzie Shaw, Bernhard Englinger, Jenna LaBelle, Hafsa M. Mire, Sibylle Madlener, Lisa Mayr, Michael A. Quezada, Maria Trissal, Eshini Panditharatna, Kati Ernst, Jayne Vogelzang, Taylor Gatesman, Matthew Halbert, Hana Pálová, Petra Pokorná, Jaroslav Štěrba, Ondřej Slabý, René Geyeregger, Aarón Díaz, Izac J. Findlay, Matthew D. Dun, Adam Resnick, Mario L. Suvà, David Jones, Sameer Agnihotri, Jessica Svedlund, Carl Koschmann, Christine Haberler, Thomas Czech, Irene Slavc, Jennifer Cotter, Keith L. Ligon, Sanda Alexandrescu, W.K. Alfred Yung, Isabel Arrillaga‐Romany, Johannes Gojo, Michelle Monje, Mats Nilsson, Mariella G. Filbin
Médium: Artigo
Jazyk:angličtina
Vydáno: 2022
On-line přístup:https://doi.org/10.1038/s41588-022-01236-3
https://www.nature.com/articles/s41588-022-01236-3.pdf
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https://doi.org/10.1038/s41588-022-01236-3
https://www.nature.com/articles/s41588-022-01236-3.pdf

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