ZFP57 regulates DNA methylation of imprinted genes to facilitate embryonic development of somatic cell nuclear transfer embryos in Holstein cows
Aberrant epigenetic nuclear reprogramming, especially imprinting pattern disorders, is one of the major causes of failure of clone development from somatic cell nuclear transfer (SCNT). Previous studies showed that ZFP57 is a key protein required for imprint maintenance after fertilization. In this...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | inglés |
Publicado: |
2022
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Acceso en liña: | https://doi.org/10.3168/jds.2022-22427 http://www.journalofdairyscience.org/article/S0022030222006683/pdf |
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