ZFP57 regulates DNA methylation of imprinted genes to facilitate embryonic development of somatic cell nuclear transfer embryos in Holstein cows

Aberrant epigenetic nuclear reprogramming, especially imprinting pattern disorders, is one of the major causes of failure of clone development from somatic cell nuclear transfer (SCNT). Previous studies showed that ZFP57 is a key protein required for imprint maintenance after fertilization. In this...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tong Yu, Ru Meng, Weijia Song, Hongzheng Sun, Quanli An, Chengtu Zhang, Yong Zhang, Jianmin Su
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2022
Mynediad Ar-lein:https://doi.org/10.3168/jds.2022-22427
http://www.journalofdairyscience.org/article/S0022030222006683/pdf
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