ZFP57 regulates DNA methylation of imprinted genes to facilitate embryonic development of somatic cell nuclear transfer embryos in Holstein cows

Aberrant epigenetic nuclear reprogramming, especially imprinting pattern disorders, is one of the major causes of failure of clone development from somatic cell nuclear transfer (SCNT). Previous studies showed that ZFP57 is a key protein required for imprint maintenance after fertilization. In this...

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Main Authors: Tong Yu, Ru Meng, Weijia Song, Hongzheng Sun, Quanli An, Chengtu Zhang, Yong Zhang, Jianmin Su
格式: Artigo
语言:英语
出版: 2022
在线阅读:https://doi.org/10.3168/jds.2022-22427
http://www.journalofdairyscience.org/article/S0022030222006683/pdf
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