Iron therapy mitigates chronic kidney disease progression by regulating intracellular iron status of kidney macrophages

Systemic iron metabolism is disrupted in chronic kidney disease (CKD). However, little is known about local kidney iron homeostasis and its role in kidney fibrosis. Kidney-specific effects of iron therapy in CKD also remain elusive. Here, we elucidate the role of macrophage iron status in kidney fib...

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Main Authors: Edwin Patiño, Divya Bhatia, Steven Z. Vance, Ada Antypiuk, Rie Uni, Chantalle A. Campbell, Carlo G. Castillo, Shahd Jaouni, Francesca Vinchi, Mary E. Choi, Oleh M. Akchurin
格式: Artigo
语言:英语
出版: 2022
在线阅读:https://doi.org/10.1172/jci.insight.159235
http://insight.jci.org/articles/view/159235/files/pdf
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