Iron therapy mitigates chronic kidney disease progression by regulating intracellular iron status of kidney macrophages

Systemic iron metabolism is disrupted in chronic kidney disease (CKD). However, little is known about local kidney iron homeostasis and its role in kidney fibrosis. Kidney-specific effects of iron therapy in CKD also remain elusive. Here, we elucidate the role of macrophage iron status in kidney fib...

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Bibliographic Details
Main Authors: Edwin Patiño, Divya Bhatia, Steven Z. Vance, Ada Antypiuk, Rie Uni, Chantalle A. Campbell, Carlo G. Castillo, Shahd Jaouni, Francesca Vinchi, Mary E. Choi, Oleh M. Akchurin
Format: Artigo
Language:English
Published: 2022
Online Access:https://doi.org/10.1172/jci.insight.159235
http://insight.jci.org/articles/view/159235/files/pdf
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