Spatial Transcriptomic Analysis of a Diverse Patient Cohort Reveals a Conserved Architecture in Triple-Negative Breast Cancer

Spatial Transcriptomic Analysis of a Diverse Patient Cohort Reveals a Conserved Architecture in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is an aggressive disease that disproportionately affects African American (AA) women. Limited targeted therapeutic options exist for patients with TNBC. Here, we employ spatial transcriptomics to interrogate tissue from a racially diverse TNBC cohort to comprehen...

Saved in:

书目详细资料
Main Authors:	Rania Bassiouni, Michael O. Idowu, Lee D. Gibbs, Valentina Robila, Pamela J. Grizzard, Michelle G. Webb, Jiarong Song, Ashley Noriega, David W. Craig, John D. Carpten
格式:	Artigo
语言:	英语
出版:	2022
在线阅读:	https://doi.org/10.1158/0008-5472.can-22-2682
标签:	添加标签没有标签, 成为第一个标记此记录!

相似书籍

Applicability of spatial transcriptional profiling to cancer research
由: Bassiouni, Rania, et al.
出版: (2021)

Applicability of spatial transcriptional profiling to cancer research
由: Rania Bassiouni, et al.
出版: (2021)

Exploring tissue architecture using spatial transcriptomics
由: Rao, Anjali, et al.
出版: (2021)

Exploring tissue architecture using spatial transcriptomics
由: Anjali Rao, et al.
出版: (2021)

Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response
由: Rohit Arora, et al.
出版: (2023)

Spatial transcriptomes within the Pseudomonas aeruginosa biofilm architecture
由: Heacock‐Kang, Yun, et al.
出版: (2017)

Spatial Transcriptome Uncovers the Mouse Lung Architectures and Functions
由: Jiang, Yujia, et al.
出版: (2022)

Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance
由: Otto, Georg W., et al.
出版: (2019)

Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
由: Hunter, Miranda V., et al.
出版: (2021)

Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
由: Miranda V. Hunter, et al.
出版: (2021)

SPACEL: deep learning-based characterization of spatial transcriptome architectures
由: Hao Xu, et al.
出版: (2023)

Spatial transcriptomes within the <i>Pseudomonas aeruginosa</i> biofilm architecture
由: Yun Kang, et al.
出版: (2017)

Decoding Heterogeneous and Coordinated Tissue Architecture in Glioblastoma Using Spatial Transcriptomics
由: Xuejiao Lv, et al.
出版: (2024)

Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer
由: Martinez, Leandro M., et al.
出版: (2019)

Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer
由: Leandro Marcelo Martinez, et al.
出版: (2019)

Uncovering an Organ’s Molecular Architecture at Single-Cell Resolution by Spatially Resolved Transcriptomics
由: Jie Liao, et al.
出版: (2020)

SOAPy: a Python package to dissect spatial architecture, dynamics, and communication
由: Heqi Wang, et al.
出版: (2025)

Comprehensive mapping of tissue cell architecture via integrated single cell and spatial transcriptomics
由: Vitalii Kleshchevnikov, et al.
出版: (2020)

Spatial transcriptomics reveals substantial heterogeneity in triple-negative breast cancer with potential clinical implications
由: Xiaoxiao Wang, et al.
出版: (2024)

The transcriptomic architecture of mouse Sertoli cell clone embryos reveals temporal–spatial-specific reprogramming
由: Cao, Feng, et al.
出版: (2013)

Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture
由: Lu, Yanfang, et al.
出版: (2021)

Integrating spatial and single-cell transcriptomics to characterize the molecular and cellular architecture of the ischemic mouse brain
由: Bing Han, et al.
出版: (2024)

Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture
由: Yanfang Lu, et al.
出版: (2021)

Single Cell and Spatial Transcriptomics Defines the Cellular Architecture of the Antimicrobial Response Network in Human Leprosy Granulomas
由: Feiyang Ma, et al.
出版: (2020)

Domain architecture conservation in orthologs
由: Forslund, Kristoffer, et al.
出版: (2011)

Domain architecture conservation in orthologs
由: Sofia K. Forslund, et al.
出版: (2011)

The architecture of the simian varicella virus transcriptome
由: Braspenning, Shirley E., et al.
出版: (2021)

The meiotic transcriptome architecture of plants
由: Dukowic-Schulze, Stefanie, et al.
出版: (2014)

Genome and Transcriptome Sequencing in Prospective Metastatic Triple-Negative Breast Cancer Uncovers Therapeutic Vulnerabilities
由: David W. Craig, et al.
出版: (2012)

Define and visualize pathological architectures of human tissues from spatially resolved transcriptomics using deep learning
由: Yuzhou Chang, et al.
出版: (2022)

Spatial transcriptomics
由: Ana C. Anderson, et al.
出版: (2022)

Decoding the Architecture of the Varicella-Zoster Virus Transcriptome
由: Braspenning, Shirley E., et al.
出版: (2020)

Decoding the Architecture of the Varicella-Zoster Virus Transcriptome
由: Shirley E. Braspenning, et al.
出版: (2020)

N-glycosylation enhances presentation of an MHC class I restricted epitope from tyrosinase
由: Ostankovitch, Marina, et al.
出版: (2009)

Quantitative contrast enhanced dual energy CT to predict avascular necrosis: a feasibility study of proximal humerus fractures
由: Hoover, Kevin B., et al.
出版: (2021)

Transcriptome architecture across tissues in the pig
由: Ferraz, André LJ, et al.
出版: (2008)

Molecules into Cells: Specifying Spatial Architecture
由: Harold, Franklin M.
出版: (2005)

Architecture of spatial circuits in the hippocampal region
由: Witter, Menno P., et al.
出版: (2014)

The spatial architecture of protein function and adaptation
由: McLaughlin, Richard N., et al.
出版: (2012)

Spatial representation and the architecture of the entorhinal cortex
由: Menno P. Witter, et al.
出版: (2006)