Role of ferroptosis on tumor progression and immunotherapy
Abstract Ferroptosis is triggered by intracellular iron leading to accumulation of lipid peroxidation consequent promotion of cell death. Cancer cell exhibits ability to evade ferroptosis by activation of antioxidant signaling pathways such as SLC7A11/GPX4 axis. In addition to transcriptional regula...
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| Main Authors: | , , , , |
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| Format: | Revisão |
| Language: | English |
| Published: |
2022
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| Online Access: | https://doi.org/10.1038/s41420-022-01218-8 https://www.nature.com/articles/s41420-022-01218-8.pdf |
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