Digoxin Derivatives Sensitize a Saccharomyces cerevisiae Mutant Strain to Fluconazole by Inhibiting Pdr5p

The poor outcome of treatments for fungal infections is a consequence of the increasing incidence of resistance to antifungal agents, mainly due to the overexpression of efflux pumps. To surpass this mechanism of resistance, a substance able to inhibit these pumps could be administered in associatio...

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Hlavní autoři: Daniel Clemente de Moraes, Ana Claudia Tessis, Rodrigo Rollin‐Pinheiro, Jefferson L. Princival, José Augusto Ferreira Perez Villar, Leandro A. Barbosa, Eliana Barreto‐Bergter, Antônio Ferreira‐Pereira
Médium: Artigo
Jazyk:angličtina
Vydáno: 2022
On-line přístup:https://doi.org/10.3390/jof8080769
https://www.mdpi.com/2309-608X/8/8/769/pdf?version=1658744323
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