Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial

This investigator-initiated, phase 2, single-arm trial primarily assessed the efficacy of G47∆, a triple-mutated, third-generation oncolytic herpes simplex virus type 1, in 19 adult patients with residual or recurrent, supratentorial glioblastoma after radiation therapy and temozolomide (UMIN-CTR Cl...

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Bibliografiske detaljer
Main Authors: Tomoki Todo, Hirotaka Ito, Yasushi Ino, Hiroshi Ohtsu, Yasunori Ota, Junji Shibahara, Minoru Tanaka
Format: Artigo
Sprog:engelsk
Udgivet: 2022
Online adgang:https://doi.org/10.1038/s41591-022-01897-x
https://www.nature.com/articles/s41591-022-01897-x.pdf
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