Development of a Novel Bilosomal System for Improved Oral Bioavailability of Sertraline Hydrochloride: Formulation Design, In Vitro Characterization, and Ex Vivo and In Vivo Studies
This study was proposed to develop an optimized sertraline hydrochloride (SER)-loaded bilosomal system and evaluate its potential for enhancement of drug oral bioavailability. A full 23 factorial design was used to prepare SER-loaded bilosomal dispersions by thin film hydration using span 60, choles...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2022
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| 在線閱讀: | https://doi.org/10.1208/s12249-022-02339-0 https://link.springer.com/content/pdf/10.1208/s12249-022-02339-0.pdf |
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