Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery
The Sleeping Beauty (SB) transposase and its newly developed hyperactive variant, SB100X, are of increasing interest for genome modification in experimental models and gene therapy. The potential cytotoxicity of transposases requires careful assessment, considering that residual integration events o...
Saved in:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2011
|
| 在线阅读: | https://doi.org/10.1093/nar/gkr384 https://academic.oup.com/nar/article-pdf/39/16/7147/16775744/gkr384.pdf |
| 标签: |
添加标签
没有标签, 成为第一个标记此记录!
|