Allosteric interactions prime androgen receptor dimerization and activation

Allosteric interactions prime androgen receptor dimerization and activation

The androgen receptor (AR) is a nuclear receptor that governs gene expression programs required for prostate development and male phenotype maintenance. Advanced prostate cancers display AR hyperactivation and transcriptome expansion, in part, through AR amplification and interaction with oncoprotei...

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Bibliográfalaš dieđut
Váldodahkkit: Elizabeth V. Wasmuth, Arnaud Vanden Broeck, Justin LaClair, Elizabeth A. Hoover, Kayla E. Lawrence, Navid Paknejad, Kyrie Pappas, Doreen Matthies, Biran Wang, Weiran Feng, Philip A. Watson, John C. Zinder, Wouter R. Karthaus, M. Jason de la Cruz, Richard K. Hite, Katia Manova‐Todorova, Zhiheng Yu, Susan T. Weintraub, Sebastian Klinge, Charles L. Sawyers
Materiálatiipa: Artigo
Giella:eaŋgalasgiella
Almmustuhtton: 2022
Liŋkkat:https://doi.org/10.1016/j.molcel.2022.03.035
https://www.cell.com/article/S109727652200291X/pdf
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https://doi.org/10.1016/j.molcel.2022.03.035
https://www.cell.com/article/S109727652200291X/pdf

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