Neurofilament Light Chain Levels in Multiple Sclerosis Correlate With Lesions Containing Foamy Macrophages and With Acute Axonal Damage

<h3>Background and Objectives</h3> To investigate whether white matter lesion activity, acute axonal damage, and axonal density in MS associate with CSF neurofilament light chain (NfL) levels. <h3>Methods</h3> Of 101 brain donors with MS (n = 92 progressive MS, n = 9 relapsin...

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Main Authors: Aletta M.R. van den Bosch, Nina L. Fransen, Matthew R. J. Mason, Annemieke Johanna Rozemuller, Charlotte E. Teunissen, Joost Smolders, Inge Huitinga
格式: Artigo
语言:英语
出版: 2022
在线阅读:https://doi.org/10.1212/nxi.0000000000001154
https://nn.neurology.org/content/nnn/9/3/e1154.full.pdf
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