Biomarker A+T−: is this Alzheimer’s disease or not? A combined CSF and pathology study

Abstract The biological definition of Alzheimer’s disease using CSF biomarkers requires abnormal levels of both amyloid (A) and tau (T). However, biomarkers and corresponding cutoffs may not always reflect the presence or absence of pathology. Previous studies suggest that up to 32% of individuals w...

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Hlavní autoři: Eleonora M. Vromen, Sterre C.M. de Boer, Charlotte E. Teunissen, Annemieke J.M. Rozemüller, Anne Sieben, Maria Bjerke, Pieter Jelle Visser, Femke H. Bouwman, Sebastiaan Engelborghs, Betty M. Tijms
Médium: Artigo
Jazyk:angličtina
Vydáno: 2022
On-line přístup:https://doi.org/10.1093/brain/awac158
https://academic.oup.com/brain/article-pdf/146/3/1166/49356410/awac158.pdf
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