Comprehensive structure and functional adaptations of the yeast nuclear pore complex

Comprehensive structure and functional adaptations of the yeast nuclear pore complex

Nuclear pore complexes (NPCs) mediate the nucleocytoplasmic transport of macromolecules. Here we provide a structure of the isolated yeast NPC in which the inner ring is resolved by cryo-EM at sub-nanometer resolution to show how flexible connectors tie together different structural and functional l...

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Hlavní autoři: Christopher W. Akey, Digvijay Singh, Christna Ouch, Ignacia Echeverria, Ilona Nudelman, Joseph M. Varberg, Zulin Yu, Fei Fang, Yi Shi, Junjie Wang, Daniel J. Salzberg, Kangkang Song, Xu Chen, James C. Gumbart, Sergey Suslov, Jay R. Unruh, Sue L. Jaspersen, Brian T. Chait, Andrej Šali, Javier Fernández-Martı́nez, Steven J. Ludtke, Elizabeth Villa, Michael P. Rout
Médium: Artigo
Jazyk:angličtina
Vydáno: 2022
On-line přístup:https://doi.org/10.1016/j.cell.2021.12.015
https://www.cell.com/article/S0092867421014537/pdf
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https://doi.org/10.1016/j.cell.2021.12.015
https://www.cell.com/article/S0092867421014537/pdf

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