Urokinase-type plasminogen activator receptor (uPAR) as a therapeutic target in cancer

Abstract Urokinase-type plasminogen activator receptor (uPAR) is an attractive target for the treatment of cancer, because it is expressed at low levels in healthy tissues but at high levels in malignant tumours. uPAR is closely related to the invasion and metastasis of malignant tumours, plays impo...

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Hauptverfasser: Bingtao Zhai, Huan Tian, Jing Sun, Junbo Zou, Xiaofei Zhang, Jiangxue Cheng, Yajun Shi, Yu Fan, Dongyan Guo
Format: Revisão
Sprache:Englisch
Veröffentlicht: 2022
Online-Zugang:https://doi.org/10.1186/s12967-022-03329-3
https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-022-03329-3
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