Mendelian randomization highlights significant difference and genetic heterogeneity in clinically diagnosed Alzheimer’s disease GWAS and self-report proxy phenotype GWAX
Until now, Mendelian randomization (MR) studies have investigated the causal association of risk factors with Alzheimer's disease (AD) using large-scale AD genome-wide association studies (GWAS), GWAS by proxy (GWAX), and meta-analyses of GWAS and GWAX (GWAS+GWAX) datasets. However, it currentl...
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Main Authors: | , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2022
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在线阅读: | https://doi.org/10.1186/s13195-022-00963-3 https://alzres.biomedcentral.com/counter/pdf/10.1186/s13195-022-00963-3 |
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