AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway
Genome editing in the lung has the potential to provide long-term expression of therapeutic protein to treat lung genetic diseases. Yet efficient delivery of CRISPR to the lung remains a challenge. The NIH Somatic Cell Genome Editing (SCGE) Consortium is developing safe and effective methods for gen...
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Hauptverfasser: | , , , , , , , , , |
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Format: | Artigo |
Sprache: | Englisch |
Veröffentlicht: |
2021
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Online-Zugang: | https://doi.org/10.1016/j.ymthe.2021.10.023 https://www.cell.com/article/S152500162100530X/pdf |
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