Exon 20 YVMA insertion is associated with high incidence of brain metastasis and inferior outcome of chemotherapy in advanced non-small cell lung cancer patients with HER2 kinase domain mutations

Exon 20 YVMA insertion is associated with high incidence of brain metastasis and inferior outcome of chemotherapy in advanced non-small cell lung cancer patients with HER2 kinase domain mutations

Chemotherapy remains the standard care for HER2 mutated advanced non-small cell lung cancer (NSCLC) even though several targeted drugs showed promising results in preliminary stages. This study aimed to investigate the association of mutation variants with clinical features and the efficacy of chemo...

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Hlavní autoři: Shuo Yang, Yan Wang, Chao Zhao, Xuefei Li, Qian Liu, Shiqi Mao, Yiwei Liu, Xiaofei Yu, Wanying Wang, Qinrun Tian, Yingying Pan, Anwen Xiong, Chen Bin, Guanghui Gao, Wei Li, Yayi He, Fengying Wu, Xiaoxia Chen, Chunxia Su, Shengxiang Ren, Caicun Zhou
Médium: Artigo
Jazyk:angličtina
Vydáno: 2021
On-line přístup:https://doi.org/10.21037/tlcr-20-559
https://tlcr.amegroups.com/article/viewFile/49582/pdf
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https://doi.org/10.21037/tlcr-20-559
https://tlcr.amegroups.com/article/viewFile/49582/pdf

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