Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy

Abstract Neuronal dysfunction due to iron accumulation in conjunction with reactive oxygen species (ROS) could represent an important, yet underappreciated, component of the epileptogenic process. However, to date, alterations in iron metabolism in the epileptogenic brain have not been addressed in...

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Main Authors: Till S. Zimmer, Bastian David, Diede W. M. Broekaart, Martin Schidlowski, Gabriele Ruffolo, A. Korotkov, Nicole N. van der Wel, Peter C. van Rijen, Angelika Mühlebner, Wim Van Hecke, Johannes C. Baayen, Sander Idema, Liesbeth François, Jonathan van Eyll, Stefanie Dedeurwaerdere, Helmut W. Kessels, Rainer Surges, Theodor Rüber, Jan A. Gorter, James D. Mills, Erwin A. van Vliet, Eleonora Aronica
格式: Artigo
语言:英语
出版: 2021
在线阅读:https://doi.org/10.1007/s00401-021-02348-6
https://link.springer.com/content/pdf/10.1007/s00401-021-02348-6.pdf
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