Complement factor B regulates cellular senescence and is associated with poor prognosis in pancreatic cancer

Abstract Background The interplay between cancer cells and stromal components, including soluble mediators released from cancer cells, contributes to the progression of pancreatic ductal adenocarcinoma (PDAC). Here, we set out to identify key secreted proteins involved in PDAC progression. Methods W...

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Hauptverfasser: Reiri Shimazaki, Shigetsugu Takano, Mamoru Satoh, Mamoru Takada, Yoji Miyahara, Kosuke Sasaki, Hideyuki Yoshitomi, Shingo Kagawa, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Kazuyuki Sogawa, Shinichiro Motohashi, Fumio Nomura, Masaru Miyazaki, Masayuki Ohtsuka
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2021
Online-Zugang:https://doi.org/10.1007/s13402-021-00614-z
https://link.springer.com/content/pdf/10.1007/s13402-021-00614-z.pdf
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