Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images

Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images

Optical Coherence Tomography (OCT) enables non-invasive imaging of the retina and is used to diagnose and manage ophthalmic diseases including glaucoma. We present the first large-scale genome-wide association study of inner retinal morphology using phenotypes derived from OCT images of 31,434 UK Bi...

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Main Authors: Hannah Currant, Pirro G. Hysi, Tomas Fitzgerald, Puya Gharahkhani, Pieter W. M. Bonnemaijer, Anne Senabouth, Alex W. Hewitt, Denize Atan, Tin Aung, Jason Charng, Hélène Choquet, Jamie E. Craig, Peng T. Khaw, Caroline C. W. Klaver, Michiaki Kubo, Jue‐Sheng Ong, Louis R. Pasquale, Charles Reisman, Maciej Daniszewski, Joseph E. Powell, Alice Pébay, Mark Simcoe, Alberta A. H. J. Thiadens, Cornelia M. van Duijn, Seyhan Yazar, Eric Jorgenson, Stuart MacGregor, Christopher J. Hammond, David A. Mackey, Janey L. Wiggs, Paul J. Foster, Praveen J. Patel, Ewan Birney, Anthony P. Khawaja
格式: Artigo
語言:英语
出版: 2021
在線閱讀:https://doi.org/10.1371/journal.pgen.1009497
https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009497&type=printable
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https://doi.org/10.1371/journal.pgen.1009497
https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009497&type=printable

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