Hypoxia-inducible factor-dependent ADAM12 expression mediates breast cancer invasion and metastasis
Significance Hypoxia (reduced oxygen availability) is a common finding in the tumor microenvironment and plays a critical role in stimulating the metastasis of breast cancer cells from the primary tumor to distant organs, which is closely related to patient mortality. Critical transcriptional respon...
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Main Authors: | , , , , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2021
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在线阅读: | https://doi.org/10.1073/pnas.2020490118 https://www.pnas.org/content/pnas/118/19/e2020490118.full.pdf |
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