Therapeutic Cancer Vaccination With a Peptide Derived From the Calreticulin Exon 9 Mutations Induces Strong Cellular Immune Responses in Patients With CALR-Mutant Chronic Myeloproliferative Neoplasms
Background: The calreticulin (CALR) exon 9 mutations that are identified in 20% of patients with Philadelphia chromosome negative chronic myeloproliferative neoplasms (MPN) generate immunogenic antigens. Thus, therapeutic cancer vaccination against mutant CALR could be a new treatment modality in CA...
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Prif Awduron: | , , , , , , , , , , , , , , , , , , , , , |
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Fformat: | Artigo |
Iaith: | Saesneg |
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2021
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Mynediad Ar-lein: | https://doi.org/10.3389/fonc.2021.637420 https://www.frontiersin.org/articles/10.3389/fonc.2021.637420/pdf |
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