Therapeutic Manipulation of Tumor-associated Macrophages: Facts and Hopes from a Clinical and Translational Perspective
The stroma of most solid tumors is populated by myeloid cells, which mostly represent macrophages. Tumor-associated macrophages (TAMs), strongly influenced by cancer cell-derived factors, are key drivers of immunosuppression and support tumor growth and spread to distant sites. Their accurate quanti...
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| Main Authors: | , , , |
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| 格式: | Revisão |
| 语言: | 英语 |
| 出版: |
2021
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| 在线阅读: | https://doi.org/10.1158/1078-0432.ccr-20-1679 https://aacrjournals.org/clincancerres/article-pdf/27/12/3291/3090153/3291.pdf |
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